Our users push iChemExplorer into new applications all the time. We started with Reaction Optimization. Then into Stability in Solution and Forced Degradation and onto Thermodynamic Solubility Screening. Our users have published in Flow Chemistry, Chiral Resolution, Crystallization, as well as Formulation and Excipient Compatibility. If temperature and stirring affect your chemistry then iChemExplorer is the best way to find out.
Publications and Presentations
- High Throughput Reaction Screening with LC/MS
- Design Of Experiment Studies
- Application of iChemExplorer in Pharmaceutical pH Stress Testing
- iChemExplorer as the Reaction Conditions Scouting Tool
- Evaluation of iChemExplorer for the Study of Bio-Catalyzed Processes
- A Systematic Design and Screening Approach for Classical Chiral Resolution in Pharmaceutical Process Development
- Reaction Path Analysis
- Crossing Reaction Boundaries with Flow Chemistry
- Shelf Life Prediction for Early Stage API by iChemExplorer
- LogD Measurement with iChemExplorer
- Genotoxic Impurities under M7 Guidelines
Application Notes and Examples
- iChemExplorer Application Note: Reaction Screening and Kinetic Study
- iChemExplorer Application Note: Reaction Control by Dosing
- iChemExplorer Application Note: Solubility vs. Temperature
- iChemExolorer Application Note: Forced Degradation for API Assessment
- iChemExplorer Application Note: pH Solubility and pKa Profiling
- iChemExplorer Application Note: Classical Chiral Resolution
- Publish Collated Report for Peak Profiles and Degradation Report
- Example Collated Report
- Coordinate Sequence Table with Temperature Control and Solubility Tool
- Example Degradation Data
- iChemExplorer Application Note: Impurity Rejection by Crystallization
- Example Degradation Report
Analytical Data from iChemExplorer available for Download
The links below provide access to data collected by users with the iChemExplorer. The data has been shared by the users to demonstrate the capability of the iChemExplorer software to review and report results of their work. The data is in .ZIP format for download. One data set includes chromatograms for over 400 samples taken through the experimental run. Be patient as the downloads may be several MB.